Genes determine potentiality but food is one of the variables that affect genetic expression of such potential. We are, what we eat.
The study in the link below describes how white rice binds LDL receptors and prevents the liver from filtering it out thereby raising cholesterol.
The key to weight loss, reducing bad cholesterol and burning fat which has been observed over and over again is to minimize eating refined carbs such as breads, pastries, rice and noodles.
If you need to cut weight to fit a dress, prepare for surgery, lower cholesterol or feel better, stop eating refined carbohydrates for a week or two.
During this time, walk 6 kilometers or 4 miles a day as fast as you can.
The difference in your body will be easily observable after a week or two.
Victor